Author
Fox Chase Cancer CenterORCID 0000-0003-2608-0128Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Aasiya Remtulla, Alison Kurimchak, Alicia Canuel…·Michael F. Olson
This study identifies MRCKα as a repressor of GEF-H1-mediated RhoA activation, promoting ovarian cancer spheroid growth and invasion.
Tong Gao, Pingfeng Zhang, Alison Kurimchak…·Jinhua Wu
The paper shows that the short Lpd isoform specifically binds Rac1 via a noncanonical helical interface, revealing a novel isoform-dependent GTPase-effector interaction.
Jason S. Wasserman, Alison Kurimchak, Carlos Herrera-Montávez…·James S. Duncan
The paper identifies a kinase-independent role of MEK1/2 in stabilizing and maturing CRAF through direct binding, independent of catalytic activity.
Anna M. Jermakowicz, Alison Kurimchak, Katherine J. Johnson…·Nagi G. Ayad
This study identifies rapid resistance to BET inhibitors in glioblastoma mediated by FGFR1 and shows that co-targeting BET and FGFR1 synergizes to reduce tumor growth.
Jason S. Wasserman, Bulat Faezov, Kishan R. Patel…·Xavier Graña
This paper identifies FAM122A as a SLiM-dependent inhibitor of B55/PP2A that competes with substrates to regulate cell cycle progression and checkpoint control.