Kalyani R. Patel

The paper characterizes hepatoblastoma with carcinoma features (HBCs) using multi-omics data, revealing their heterogeneous composition, worse outcomes, and origin from arrested HB cells due to WNT signaling.

This paper introduces a method to increase the proportion of correctly repaired hepatocytes in the liver through transient gene inhibition and transgene delivery, achieving a 25% increase in targeted cells and five-fold transgene expression.

This paper develops an ICG-based liquid biopsy test to detect circulating tumor cells in pediatric liver cancer patients, showing that CTC burden correlates with therapy response.