BioinformaticsbioRxivPreprint
Integrated optimization of experimental and computational workflows improves genome recovery in long-read gut metagenomics
DOI 10.64898/2026.05.22.727065
Author
Tao Zhang
BGI Group (China)ORCID 0000-0003-2765-2802Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2019-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship9 papers
Recent·Most cited
- MicrobiologymBioPeer-reviewed
Unraveling the impact of host genetics and factors on the urinary microbiome in a young population
Leying Zou, Zhe Zhang, Junhong Chen…·Xiaomin Liu
This study characterizes the urinary microbiome in 1579 Chinese individuals, identifying host factors and genetic associations that influence microbial composition and urotype classification.
17 citationstop 2% - Developmental BiologyScientific ReportsPeer-reviewed
Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal-fetal interface
Quanlei Wang, Jinlu Li, Shengpeng Wang…·Zhouchun Shang
The paper uses single-cell transcriptomics to analyze cellular and molecular differences across maternal-fetal sections of the placenta, identifying key cell types and regulatory factors involved in placental development and preeclampsia.
- Genetic & Genomic MedicinemedRxivPreprint
iGWAS: image-based genome-wide association of self-supervised deep phenotyping of human medical images
Ziqian Xie, Tao Zhang, Sangbae Kim…·Degui Zhi
The paper introduces iGWAS, a method using self-supervised deep learning to extract phenotypes from medical images for GWAS, finding new genetic loci related to retinal vessel development.
- GeneticsNature GeneticsPeer-reviewed
Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome
Xiaomin Liu, Xin Tong, Yuanqiang Zou…·Tao Zhang
This study uses Mendelian randomization to identify causal relationships between gut microbiome composition and blood metabolites in a Chinese cohort.
373 citationstop 1% - GeneticsCell DiscoveryPeer-reviewed
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome
Xiaomin Liu, Xin Tong, Jie Zhu…·Tao Zhang
This study identifies genetic loci associated with the oral microbiome using metagenome-genome-wide association studies in over 1,915 individuals.
122 citationstop 1% - GeneticsCell DiscoveryPeer-reviewed
M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases
Xiaomin Liu, Shanmei Tang, Huanzi Zhong…·Tao Zhang
This paper performs M-GWAS on a Chinese cohort to identify genetic contributions to the gut microbiome and its associations with complex diseases.
70 citationstop 3% - Genetic & Genomic MedicineCell DiscoveryPeer-reviewed
Initial Whole Genome Sequencing and Analysis of the Host Genetic Contribution to COVID-19 Severity and Susceptibility
Fang Wang, Shujia Huang, Rongsui Gao…·Lei Liu
This study analyzes whole-genome sequencing data from 332 Chinese COVID-19 patients to identify genetic variants associated with disease severity and susceptibility.
226 citationstop 1% - GeneticsAnnals of the Rheumatic DiseasesPeer-reviewed
Sequencing of the MHC region defines HLA-DQA1 as the major independent risk for anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis in Han population
Jianping Guo, Tao Zhang, Hongzhi Cao…·Zhanguo Li
This study identifies HLA-DQA1 as the major independent genetic risk for ACPA-positive RA in Han population through MHC region sequencing and HLA-typing.
39 citationstop 5%