Author

Wen Chen

South China University of TechnologyORCID 0000-0003-2956-5462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrej LuptákiD· 1 shared Brandon LatifiiD· 1 shared Christopher D. Sibley· 1 shared Guangyu ZhouiD· 1 shared Ivy (Jing) Wu· 1 shared Jennifer A. PrescheriD· 1 shared John S. SchneeklothiD· 1 shared Li C. Xia· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Andrej LuptákORCID

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2 papers

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedDec 6, 2024

Bioorthogonal cyclopropenones for investigating RNA structure

Wen Chen, Christopher D. Sibley, Brandon Latifi…·Jennifer A. Prescher

This paper develops bioorthogonal cyclopropenones to crosslink RNA and study its native structures in cells.

3 citations

experimental assay

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BiochemistryInternational Journal of Biological MacromoleculesPeer-reviewedFeb 12, 2024

Molecular mechanism of NAD+ binding to the Nudix homology domains of DBC1

Liming Ou, Xuechen Zhao, Ivy (Jing) Wu…·Wen Chen

This study investigates how NAD+ binds to DBC1's Nudix homology domains using NMR, ITC, and molecular docking, revealing key residues and binding affinity.

1 citation

humanproteomics

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