Lydie Cheval

This study shows GDF15 helps mice and humans maintain potassium levels by promoting intercalated cell proliferation in response to aldosterone excess.

This study identifies Gdf15 as a key mediator of lithium-induced collecting duct dysfunction and remodeling, linking spatial stress responses to functional and structural kidney injury.

This study identifies biomechanical changes in the tubular basement membrane as drivers of cyst formation in ADPKD, linking cilia and polycystin-1 function.

The paper identifies type A intercalated cells as critical for Na+ secretion in response to high salt diets and shows their absence leads to a Bartter-like phenotype.

This study shows that low lithium exposure in rats causes microcystic dilations of collecting ducts without inducing nephrogenic diabetes insipidus.