Author

Alexandre G. Casanova

Centre National de la Recherche ScientifiqueORCID 0000-0003-2988-2046Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nicolas ReynoirdiD· 2 shared Adit GangulyiD· 1 shared Albino BacollaiD· 1 shared Ana Morales BeniteziD· 1 shared Andrés PalenciaiD· 1 shared Chuan HeiD· 1 shared Clément OyeniraniD· 1 shared Ekaterina Bourova-FliniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Nicolas ReynoirdORCID

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2 papers

Recent·Most cited

Cancer BiologyCell DiscoveryPeer-reviewedJan 31, 2024

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis

Alexandre G. Casanova, Gaël S. Roth, Simone Hausmann…·Nicolas Reynoird

This study identifies SMYD2 as a master regulator of breast cancer metastasis and shows that targeting the SMYD2-BCAR3-FMNL axis can prevent metastatic spread.

30 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintAug 28, 2020

Aberrant RNA methylation triggers recruitment of an alkylation repair complex

Joshua R. Brickner, Ning Tsao, Rebecca Rodell…·Nima Mosammaparast

The paper shows RNA alkylation triggers recruitment of the ASCC repair complex via RNF113A, revealing RNA damage as a signal for DNA repair.

1 citation

humanDNA methylation

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