Daniel P. Nussbaum

The paper introduces Suco and Compocyte to classify immune cells from 3,965 patients, identifying new macrophage and monocyte states and T cell memory erosion in metastases.

This paper uses spatial transcriptomics to identify low-risk and high-risk expression programs in IPMN that correlate with exocrine and basal-like PDAC signatures, improving risk stratification.

This study profiles the pancreatic microbiome in patients with benign, precancerous, and cancerous conditions, finding a low-biomass, low-diversity microbiome that does not differ across disease states.