Matthew K. Iyer

This study develops an immunocompetent mouse model of liposarcoma that recapitulates human tumor subtypes and immune features, enabling preclinical immunotherapy research.

This paper uses spatial transcriptomics to identify low-risk and high-risk expression programs in IPMN that correlate with exocrine and basal-like PDAC signatures, improving risk stratification.

This study profiles the pancreatic microbiome in patients with benign, precancerous, and cancerous conditions, finding a low-biomass, low-diversity microbiome that does not differ across disease states.