Andreas H. Brunner

This study uses nanoscale DNA tracing to show that mitotic chromosomes form through self-organization via large, overlapping loops driven by Condensins.

The paper shows Cohesin replaces Condensin to rebuild genome architecture after mitosis, forming nested loop structures.

This study shows Ki-67 switches from repelling to attracting chromosomes during mitotic exit, forming a liquid-like coat that drives chromosome clustering through phase separation.