David M. Brandman

This study shows that speech motor cortex encodes sentence-level linguistic structure and semantic content through single-unit activity in three BrainGate2 participants.

This paper fine-tunes an ASR model on human-transcribed synthesized speech to better align its word error rate with human perception, achieving higher correlation than zero-shot ASR.

This paper introduces a multi-user transformer-based decoder for intracortical speech BCIs, achieving lower word error rates with less training data than individual models.

Brain2voice 2.0 improves voice synthesis from neural signals, achieving 5.24% word error rate, 8x better than prior methods, enabling real-time intelligible speech for paralyzed individuals.

A paralyzed man with ALS used a long-term intracortical BCI for over two years to communicate, control a computer, and work independently.

This paper tests deep neural ensembles in real-time speech BCIs, showing reduced word error rates and introducing a computationally efficient pseudoensembling method.

The paper shows that premotor cortex uses a compositional neural geometry to plan words by combining phoneme representations, enabling efficient planning of novel sequences.

This study decodes speech mode and loudness from ventral precentral gyrus activity in two participants, achieving high accuracy in predicting speech parameters and developing a closed-loop decoder for expressive speech neuroprostheses.

This paper demonstrates cross-brain transfer learning for intracortical BCIs decoding speech and handwriting, showing improved performance with limited training data and specific decoder design.

This paper decodes intended speech from a person with anarthria and locked-in syndrome using an intracortical brain-computer interface, showing that phonemes, words, and higher-order language units can be decoded above chance.

This paper demonstrates a brain-to-voice neuroprosthesis that synthesizes speech from neural activity, enabling real-time voice modulation with closed-loop feedback.

The paper shows error detection signals in speech motor cortex during neuroprosthesis use, enabling error identification with 86% accuracy and revealing distinct patterns for different error types.

This paper demonstrates that neural activity from ventral motor cortex can enable high-performance cursor control and click for brain-computer interfaces.

The paper studies neural encoding of inner speech in motor cortex and shows it can be decoded, but also identifies a neural dimension that can prevent unintentional decoding of private thoughts.

The paper maps human motor cortex using microelectrode recordings, finding whole-body representations and challenging the traditional motor homunculus model.

BRAND provides a platform for closed-loop experiments with deep networks, achieving low latency and supporting multiple programming languages.

The paper introduces SIMNETS, a framework to map computational similarity of neurons in large-scale recordings, identifying subnetworks and validating cluster significance.

This study decodes English words from neural activity in macaques' secondary auditory cortex using spike-based machine learning, showing the auditory cortex processes complex sounds as a distributed network.