Thorsten Hugel

This study identifies conserved residues in ArlJ that interact with ArlI to generate torque during archaellum rotation using TIRF microscopy and structural analysis.

This paper introduces FRET-TTB, a method to track transfected biomolecules in living cells, showing it can measure conformational changes and localization with single-molecule resolution.

This study shows TAF2's intrinsically disordered region drives condensation in nuclear speckles, recruiting SRRM2 to TFIID and affecting alternative splicing.

The paper introduces SMACKS, a method to extract kinetic rates and thermodynamic quantities from single molecule data without assuming equilibrium or prior models.