Author

Sichao Huang

Harbin Medical UniversityORCID 0000-0003-3292-4577Unclaimed ORCID profile · follow to get notified of new preprints

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Sichao Huang2 papers · Harbin Medical University

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

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Bin SuniD· 1 shared Manjie ZhangiD· 1 shared Qian ZhangiD· 1 shared Te LiuiD· 1 shared Yu XiaiD· 1 shared

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1 shared paperBiophysics

Bin SunORCID

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1 paper

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BiophysicsPLoS Computational BiologyPeer-reviewedFeb 7, 2024

Reconciling ASPP-p53 Binding Mode Discrepancies through an Ensemble Binding Framework that Bridges Crystallography and NMR Data

Te Liu, Sichao Huang, Qian Zhang…·Bin Sun

This study reconciles discrepancies in ASPP-p53 binding modes by showing that an ensemble of simulated complexes better aligns with experimental data than single crystal structures.

DOI 10.1371/journal.pcbi.1011519

structural biologydeep learning

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