Author

Lihua Chen

Guangzhou LaboratoryORCID 0000-0003-3369-1875Unclaimed ORCID profile · follow to get notified of new preprints

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Lihua Chen3 papers

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Beidong LiuiD· 1 shared Deqi CheniD· 1 shared Feng ZhangiD· 1 shared Haopeng LiniD· 1 shared Huisheng LiuiD· 1 shared Jiawei Yan· 1 shared Jiaxiang YiniD· 1 shared Joris WinderickxiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Beidong LiuORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedDec 21, 2025

Restoration of PKM1 improves functional maturation of human stem-cell derived-β cell by regulating PEP metabolism

Haopeng Lin, Xin Liu, Feng Zhang…·Huisheng Liu

This study identifies PKM1-regulated PEP metabolism as a key factor in improving functional maturation of human stem-cell derived β cells by enhancing calcium response and insulin secretion.

3 citations

humanbulk RNA-seq

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Cell BiologybioRxivSep 27, 2023

Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids

Xiuling Cao, Xiang Wu, Lei Zhao…·Beidong Liu

The paper identifies sphingolipids as regulators of synphilin-1 inclusion body maturation and detoxification in yeast and mammalian cells.

3 citations

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