Xingyu Fang

EukaUTR is a foundation model for eukaryotic 3' UTRs that predicts function and generates new sequences with regulatory properties.

CodonMamba is a foundation model for mRNA coding sequence design that achieves state-of-the-art performance and enables programmable codon optimization through inference-time steering.

UTRGen is a unified framework for designing mRNA 5' UTRs that integrates sequence generation, prediction, and function-guided optimization, achieving state-of-the-art performance across multiple tasks.

The paper uses microarray analysis to identify differentially expressed genes in cervical cancer cells after modulating miR-205 and miR-141, revealing potential pathways and gene regulation.