Sebastian Overmans

This study investigates sesquiterpenoid production in Chlamydomonas reinhardtii by expressing patchoulol synthase in different subcellular compartments and optimizing carbon sources to maximize yield.

This paper engineers isoprene production in Chlamydomonas reinhardtii using herbicide resistance markers and CO2-fed cultivation optimization to generate biomass and isoprene from wastewater.

The paper investigates using metal-organic frameworks (MOFs) to elicit secondary metabolite accumulation in Aquilaria crassna callus cultures, finding that certain MOFs significantly increase metabolite production.

The paper compares UV-B radiation resistance between Synechococcus and pico-eukaryotic phytoplankton in the Red Sea, finding Synechococcus more resilient.

This paper develops a solvent-free method using functionalized silica particles to extract terpenoids from microalgae, showing potential for large-scale applications due to safety and reusability advantages.

This paper introduces a rapid transformation protocol and tools for metabolic engineering in Cyanidioschyzon merolae, demonstrating isoprene production using a synthetic plasmid toolkit.

This paper demonstrates the production and functionalization of heterologous sesquiterpenoids in the plastid of Chlamydomonas reinhardtii using STPs and soluble CYPs, achieving up to 80% functionalization and 250-2500 µg L-1 yields.

This paper develops a sustainable method to produce agarwood-like sesquiterpenoids using synthetic biology in algae, avoiding the need for harvesting endangered trees.

This paper compares 15 solvents for in situ extraction of hydrocarbons from Botryococcus braunii, finding that bio-based terpenes recover more hydrocarbons than alkanes, but all tested solvents were toxic to the algae.

The paper demonstrates that synthetic perfluorocarbon liquids can serve as effective physical sinks for isoprenoid metabolites produced by microbial cultures, offering advantages over traditional hydrocarbon solvents.