Katherine J. Picott

This study identifies key residues in CfrA that alter substrate preference through targeted mutagenesis, showing that two mutations can shift substrate specificity to dichloroethane.

This study compares the kinetic properties of three closely related chloroalkane reductive dehalogenases, revealing distinct substrate preferences and inhibition sensitivities with implications for bioremediation.

The paper identifies functional genes in a microbial consortium that dechlorinates chloroform to dichloromethane and mineralizes dichloromethane, using metagenomic and metaproteomic analysis.