Molecular BiologyNucleic Acids ResearchPeer-reviewed
Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes
James M. Burke, Rodney P. Kincaid, Francesca M. Aloisio…·Christopher S. Sullivan
The paper develops a compact shRNA expression system using retroviral miRNA gene architecture, reducing coding space needed for shRNA expression by over two-fold compared to U6/H1 promoters.