Johanna Strobl

This study identifies reduced tissue-resident memory T cells and increased PD-1 expression in the KS tumor microenvironment of HIV-positive individuals, suggesting impaired antitumor immunity and potential for immune checkpoint therapy.

The paper constructs a scRNA-seq atlas of chronic inflammatory skin diseases by integrating datasets from 27 diseases, identifying shared and disease-specific inflammatory signatures.

This study shows that EGFR protects hair follicle stem cells from immune-mediated damage by maintaining JAK-STAT1-sensitive immune privilege, and its disruption leads to scarring hair loss, which can be reversed by JAK1/2 inhibition.

The paper identifies Th2-like malignant cells in CTCL supported by a B cell-rich microenvironment through single-cell and spatial transcriptomics analysis.