Author

Lucas D. Caeiro

University of MiamiORCID 0000-0003-3677-7279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Carolina P. Bañuelos· 2 shared Lluís MoreyiD· 2 shared Ramiro E. VerdúniD· 2 shared Daniel BilbaoiD· 1 shared Daniel Bilbao Cortes· 1 shared Diana Domínguez· 1 shared Felipe BeckedorffiD· 1 shared Ho Lam ChaniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Carolina P. Bañuelos

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 28, 2025

Bypass of Blocking Lesions by RNAPII Impairs the Transcriptional DNA Damage Response

Carolina P. Bañuelos, Lucas D. Caeiro, Pradeep Reddy Cingaram…·Ramiro E. Verdún

The paper shows that RNAPII bypassing DNA lesions, regulated by p300, leads to genome instability and reduced cell proliferation.

DOI 10.1101/2025.04.28.651040

humanDNA methylation

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Cancer BiologybioRxivNov 6, 2023

Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma.

Lucas D. Caeiro, Yuichiro Nakata, Rodrigo L. Borges…·Lluís Morey

This study shows that H3K36M mutations in HNSCC create a therapeutic window by altering H3K27me3 levels, making tumors sensitive to PARP1/2 inhibitors or their combination with H3K27me3-upregulating agents.

12 citations

humanDNA methylation

𝕏 PostBluesky