Tránsito García‐García

This study identifies how a single mutation in the Omicron variant of SARS-CoV-2's ORF3a protein alters its host-cell remodelling effects, shifting from lipid accumulation to preserving Golgi structure.

This study shows that SARS-CoV-2 ORF7a causes mitochondrial dysfunction by activating PDK4 and inhibiting complex I, altering host metabolism.

This study shows that SARS-CoV-2 accessory proteins ORF3a and ORF9b suppress monocytic inflammatory responses, with Omicron variants enhancing this effect.

This study uses TraDIS to identify conditionally essential genes in Salmonella Typhimurium during porcine infection, revealing niche-specific and conserved fitness requirements.

This study uses scRNA-seq to analyze immune cell changes in porcine ileum during Salmonella Typhimurium infection, revealing altered cell composition and immunometabolic responses.

The paper develops a cellular platform using SARS-CoV-2 ORF-expressing A549 cells to screen anti-inflammatory compounds from Fasciola hepatica, showing FhNEJ extract reduces IL11 levels.

This study identifies mitochondrial and metabolic reprogramming induced by SARS-CoV-2 accessory proteins in lung cells, revealing potential therapeutic targets.