BiochemistryNature Structural & Molecular BiologyPeer-reviewed
The p97/VCP adapter UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions
Julian R. Braxton, Chad R. Altobelli, Maxwell R. Tucker…·Daniel R. Southworth
This study identifies UBXD1 as a p97 ATPase inhibitor and shows how its domains induce structural remodeling and ring opening of the p97 hexamer.
18 citations