Petros Daras

AntiSite predicts antibody and nanobody paratopes using shared models with or without structural data, achieving high performance across benchmarks and generalizing to nanobodies.

The paper identifies an interaction site between ATXN1 and MED15 and shows that targeting this site with a chemical compound reduces polyQ-expanded protein dimerization in SCA1.

ParaSurf improves paratope prediction by integrating surface geometry and non-geometric factors, achieving state-of-the-art results across multiple metrics.