Alexander Kuzmin

The paper discovers a flavin-based fluorescent protein, LSSFbFP, with a large Stokes shift, achieved through excited state proton transfer, and validates its mechanism using spectroscopy and crystallography.

The paper presents a high-throughput algorithm using AlphaFold to predict F-Type ATP synthase rotor ring stoichiometries from 8 to 27 protomers, validated with molecular dynamics simulations.

This paper describes the engineering of soluble bacteriorhodopsin analogues and reports their crystal structure, demonstrating the potential of protein engineering for developing molecular tools.

The paper tests ProteinMPNN's ability to reengineer a flavin-binding fluorescent protein, showing it can generate variants with similar properties to the original.

The paper uses spectroscopy and X-ray structures to reveal two distinct mechanisms by which flavin-binding proteins tune their fluorescence spectra.