Author

Soumajit Dutta

University of Illinois Urbana-ChampaignORCID 0000-0003-3951-8088Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Diwakar ShuklaiD· 2 shared Lawrence ZhaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersBiophysics

Diwakar ShuklaORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Biological ChemistryPeer-reviewedApr 8, 2026

Dynamic Mechanism for Subtype Selectivity of Endocannabinoids

Soumajit Dutta, Lawrence Zhao, Diwakar Shukla

This study investigates the biophysical mechanisms underlying anandamide selectivity for CB1 receptors, revealing enthalpic and entropic effects shaped by N-terminus movements and binding pocket volume differences.

1 citation

humanstructural biology

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BiophysicseLifePeer-reviewedJul 26, 2024

Characterization of binding kinetics and intracellular signaling of new psychoactive substances targeting cannabinoid receptor using transition-based reweighting method

Soumajit Dutta, Diwakar Shukla

This study uses simulation and machine learning to analyze how new psychoactive substances interact with cannabinoid receptors, revealing structural differences that lead to stronger beta-arrestin signaling and adverse effects.

6 citations

humanmultiome

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