Olivier Clermont

This study examines how iron uptake systems affect cefiderocol activity in E. coli, showing that the fec operon increases resistance and is linked to virulence.

The paper identifies a residence-colonization trade-off and niche differentiation among E. coli phylogroups in healthy humans, enabling their coexistence through equalizing and stabilizing mechanisms.

This study tracks E. coli dynamics in a human gut over 20 years, showing how strain properties and environmental factors influence diversity and persistence.

This paper predicts phage-bacteria interactions at the strain level using genomic data from Escherichia isolates and shows tailored phage cocktails are more effective.

The paper reports the first inter-phylum transfer of an ESBL-encoding gene, blaMUN-1, between Bacteroidota and Pseudomonadota, highlighting rare but possible horizontal gene transfer events.

This study analyzes the genomic evolution of commensal E. coli over 30 years in France, finding increases in virulence and antibiotic resistance genes through clonal expansion and gene frequency changes within clones.

This study assesses gene essentiality across diverse E. coli strains and growth conditions, revealing that essentiality varies independently of phylogeny and is influenced by mobile genetic elements.

The paper predicts growth defects in Escherichia coli strains using genetic variant impact models and gene function data, achieving reliable predictions for up to 38% of tested conditions.