Author

Lavinia J. González Aparicio

Washington University in St. LouisORCID 0000-0003-3994-9291Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Carolina B. LópeziD· 1 shared Matthew HackbartiD· 1 shared Yanling YangiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

Carolina B. LópezORCID

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1 paper

Recent·Most cited

MicrobiologyPLoS BiologyPeer-reviewedNov 20, 2023

Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity

Lavinia J. González Aparicio, Yanling Yang, Matthew Hackbart, Carolina B. López

This study shows that copy-back viral genomes (cbVGs) induce cellular stress responses, including stress granules and translation inhibition, during RSV and parainfluenza virus infections, which reduce viral protein expression without affecting antiviral immunity.

14 citations

humanspatial transcriptomics

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