Rolf Kümmerli

The paper combines experimental and bioinformatic methods to assess amino acid auxotrophy in 315 Pseudomonas isolates, finding most are prototrophic with few auxotrophs and multiple biosynthesis pathways.

The paper shows that cyanobacterial siderophore cyanochelin B is used by distant heterotrophs under iron limitation, supporting microbial interactions in soil crust ecosystems.

The paper tracks eco-evolutionary dynamics in lung pathobiomes of children with cystic fibrosis, finding that P. aeruginosa variants reduce antagonism towards other pathogens, potentially stabilizing communities.

This study shows that siderophore-producing Pseudomonas strains inhibit Legionella pneumophila growth by limiting iron availability through siderophore-mediated competition.

This study shows that Escherichia coli can evolve resistance to the predatory bacterium Bdellovibrio bacteriovorus through changes in outer membrane proteins, with fitness costs.

This paper shows that Staphylococcus aureus uses both genetic and phenotypic changes to resist inhibitory molecules from Pseudomonas aeruginosa.

The paper develops a co-evolution algorithm to predict bacterial iron interaction networks based on siderophore synthetase-receptor gene pairs across Pseudomonas genomes, revealing habitat- and pathogen-specific interactions.

This study shows that strain identity has a greater impact on Pseudomonas community functioning than strain interactions in terms of productivity and siderophore production.

This study uses microscopy to examine interactions between Pseudomonas aeruginosa and six opportunistic pathogens, revealing a range of ecological interactions from mutualism to antagonism.

The paper develops a bioinformatic pipeline to predict bacterial siderophore structures and receptors from genome sequences, revealing significant diversity in pyoverdines and their receptors.

The paper develops a protocol for multispecies bacterial infections in zebrafish and an automated image analysis pipeline to monitor them.

This study develops a random forest classifier to identify body fluids from complex crime scene stains using microbiome data, achieving an F1 score of 0.89 on forensic samples.

This study examines how pyoverdine and ceftazidime interact with E. coli resistance evolution, showing combination treatment reduces resistance development.

The paper shows that pyoverdine, a siderophore produced by Pseudomonas aeruginosa, protects bacterial communities from UV damage by acting as a public sunscreen.

This study manipulates virulence factor availability in Pseudomonas aeruginosa within an insect host and finds that it affects virulence and bacterial fitness in complex, non-linear ways.

This study uses meta-analysis to assess the role of pyoverdine, a virulence factor in Pseudomonas aeruginosa, across different infection models, finding its effect varies significantly and is rarely essential for infections.