Author
King's College LondonORCID 0000-0003-4119-5337Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Chang Lu, Jan Maciej Zaucha, Rihab Gam…·Julian Gough
The paper presents a genetics-first framework using molecular knowledge to predict phenotypes from rare coding variants in a direct-to-consumer genotype cohort, identifying novel genetic causes for developmental disorders.
Kenneth T. Walker, Matthew Donora, Anthony Thomas…·Thomas Meany
The paper introduces CONTAIN, an automated RT-qPCR COVID-19 testing system based on a shipping container, achieving 2400 tests/day using open-source robotics and validated with synthetic and patient samples.
Mukul Tewary, Dominika Dziedzicka, Joel Östblom…·Peter W. Zandstra
The paper develops an in vitro platform to study fate patterning in hPSCs, revealing Nodal-dependent switches between gastrulation and neurulation-associated gene profiles.
Alessandra Vigilante, Anna Laddach, Nathalie Moens…·Fiona M. Watt
The paper integrates genetic and cell biological data from human iPSC lines to identify intrinsic and extrinsic factors driving inter-individual variability in cell behavior.
Helena Kilpinen, Angela Goncalves, Andreas Leha…·Daniel J Gaffney
This study analyzes 522 human iPSCs to identify genetic sources of phenotypic variation, finding 5-25% of variation in traits like differentiation capacity is due to individual differences.