Morten Simonsen Dueholm

The paper identifies a novel Saccharimonadia genus associated with a polyphosphate-accumulating bacterium in wastewater treatment plants and explores their ecological and metabolic interactions.

The paper constructs a global genome catalog of 53,501 long-read MAGs from activated sludge, representing 12,047 prokaryotic species and enabling analysis of functional traits and ecological roles in wastewater treatment systems.

Savont improves ASV recovery from long-read amplicon sequencing with high accuracy and lower sequencing depth.

This study shows that Oxford Nanopore Technologies can generate amplicon sequence variants (ASVs) directly from raw reads, enabling high-resolution microbial community profiling without reliance on reference databases.

epsSMASH identifies exopolysaccharide biosynthetic gene clusters in environmental and human microbiomes, revealing widespread uncharacterized clusters.

Microflora Danica compiles 10,686 shotgun metagenomes and 449 rRNA datasets to create an atlas of Danish environmental microbiomes, revealing hidden homogeneity and novel nitrifiers.

The paper uses activity-targeted metaproteomics to study rare syntrophic bacteria in anaerobic communities, revealing their metabolic activity and a previously hypothesized oxidative glycine pathway.

This study determines the structural basis of FapC biofilm formation in Pseudomonas aeruginosa using integrative structural biology methods.

The paper investigates denitrifying protist endosymbionts in wastewater treatment plants, finding their presence in 20-50% of facilities and highlighting temporal fluctuations and incomplete denitrification pathways.

The paper predicts secreted proteomes of activated sludge microorganisms to identify nutrient niches, finding distinct enzyme profiles among microbial taxa.

This study benchmarks long-read sequencing and ASV-resolving tools for accurate rRNA operon recovery from environmental microeukaryotes using a synthetic mock community.

The paper expands the MiDAS database with global anaerobic digester microbiome data, revealing environmental influences on microbial communities and identifying core taxa.

The paper improves 16S rRNA gene primers to better detect Patescibacteria in wastewater treatment plants, revealing their global diversity and potential ecological roles.

This paper introduces an experimental method to isolate previously uncultured microbial species from activated sludge using 16S rRNA gene amplicon sequencing, resulting in the cultivation of 102 strains from 200 colonies.

This study shows that overexpression of human alpha-synuclein in rats leads to gut microbiome dysbiosis, altered metabolites, and aging-related changes that can be modulated by antibiotics.

This study characterizes Chloroflexota in wastewater treatment plants globally, identifying novel taxa and their ecological roles in carbon and nutrient cycling.