Ángel Nadal

This study shows that selective activation of estrogen receptors ER and ERβ modulates electrical activity and reduces basal insulin secretion in human EndoC-βH1 cells through extranuclear mechanisms.

This study identifies increased TGFβ/Activin-Smad2 signaling in GDM as a contributor to β-cell dysfunction and glucose intolerance, with pharmacological inhibition showing therapeutic potential.