Jiajie Diao

This paper develops CyMA, small peptides that disrupt cancer cell Golgi function by exploiting enzymatic cycles, showing selectivity over hepatocytes and immune cells.

This study develops OptoMitoTether, an optogenetic system to control mitochondrial proximity, which increases membrane potential and reduces blue light-induced damage in cells and C. elegans.

This study identifies tonic signaling as a key factor in CAR-T cell efficacy for diffuse midline glioma, showing that restrained tonic signaling improves therapeutic outcomes.

The paper reveals how NSF and SNAP proteins remodel SNARE complexes to enable synaptic transmission by disassembling syntaxin clusters through ATP hydrolysis.

This study shows that N-acetylation of α-synuclein enhances its ability to cluster synaptic vesicles via increased interaction with lysophosphatidylcholine.

This study investigates how lipid phases in synaptic vesicle membranes regulate the structure and function of the VAMP2 SNARE motif using in-cell NMR and lipidomic profiling.

The paper analyzes 5-hydroxymethylcytosine in cell-free DNA to predict tumor types and stages with high accuracy.