Caitlin M. Davis

msaGUI is a no-code tool for analyzing and visualizing multispectral images through customizable workflows and exportable outputs.

The paper uses optical photothermal infrared imaging to study palmitic acid metabolism in live cells, revealing diacylglycerol intermediates and gel phase changes in the ER.

This paper demonstrates the incorporation of L-cyanohomoalanine into proteins in E. coli and evaluates its labeling efficiency and stability compared to methionine and azidohomoalanine.

This paper uses machine learning to classify subcellular organelles from infrared images, achieving accurate identification of several organelles but not all.

The paper investigates how a Vibrio cholerae peptide binds lipids through a β-hairpin conformation, contributing to biofilm adhesion and host colonization.

This study investigates how PEG-induced phase separation affects FRET-based crowding sensors, showing that CrH2 forms puncta while CrD does not, and identifies biophysical mechanisms behind the sensor response.

This study investigates how phase separation affects the stability and dynamics of G-quadruplex and i-motif DNA structures in living cells.

The paper shows that weak specific protein interactions in cellular compartments determine barnase stability, differing from in vitro and artificial crowding conditions.

This study evaluates OPTIR for biological imaging, showing multifrequency imaging matches hyperspectral imaging speed and demonstrating IR probe utility across cell lines and organisms.

The paper uses isotopically labelled oleic acid and glucose to measure lipogenesis rates in adipocytes and hepatocytes, finding oleic acid inhibits de novo lipogenesis in hepatocytes but not adipocytes.

The paper identifies PFKL interactors at specific interfaces and shows compartmentalization reduces interactions at interface 2.