Samantha L. Wilson

This study identifies 8% O2 as a physiologically relevant oxygen condition and 24 h of severe hypoxia as a paradigm to model PE-associated syncytiotrophoblast dysfunction in vitro.

This study identifies subtle transcriptional changes in murine placentae following prenatal cannabis smoke exposure, affecting metabolic, transport, and regulatory pathways.

This study identifies transcriptional and isoform-level regulation changes in preeclamptic placentas, revealing sex-specific patterns and novel isoform switches linked to dyslipidemia.

The paper uses cfMeDIP-seq to analyze cell-free placental DNA methylation in maternal plasma, identifying enriched regions associated with preterm birth and IUGR.

This study examines sex-specific DNA methylation and variability differences in placental tissue between IVF and spontaneous pregnancies, identifying significant shifts in variability and cell composition.

This paper introduces synthetic spike-in controls for cfMeDIP-seq to enable accurate and reproducible quantification of DNA methylation, reducing batch effects and technical biases.

This study identifies DNA methylation changes in early-onset preeclampsia, late-onset preeclampsia, and normotensive intrauterine growth restriction, revealing distinct methylation clusters and potential clinical subgroups.