Stewart N. Loh

This paper develops ATOM biosensors using mStayGold and mBaoJin to detect PSD95, Gephyrin, and HOMER1 with high specificity and turn-on ratios over 100-fold.

This study shows that kidney-like flow shear in microfluidic devices efficiently induces LECT2 aggregation, with the I40V mutation enhancing fibril formation and aggregate size.

The paper develops ATOM biosensors that activate fluorescence upon target binding, enabling multiplexed detection of proteins in live cells with high specificity.

This paper describes the engineering of a DNA-activated protein switch, nLuc-AFF, which can be used as a biosensor for DNA/RNA sequences, serotonin, ATP, and as a computational device processing DNA inputs.