Author

Helvijs Niedra

Latvian Biomedical Research and Study CentreORCID 0000-0003-4396-4021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Rihards SaksisiD· 3 shared Vita RovīteiD· 3 shared Aija Geriņa-Bērziņa· 2 shared Aldis PuķītisiD· 2 shared Jurijs Nazarovs· 2 shared Marta Līva SpriņģeiD· 2 shared Natalja Senterjakova· 2 shared Raitis PečulisiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Rihards SaksisORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 1, 2026

Spatial organization of myofibroblastic and complement-secreting CAFs in neuroendocrine tumors

Helvijs Niedra, Marta Līva Spriņģe, Katrine Tiltina…·Vita Rovīte

The paper uses spatial transcriptomics to analyze stromal microenvironments in neuroendocrine tumors, identifying spatially segregated fibroblast states across different anatomical sites.

DOI 10.64898/2026.02.26.708188

humanspatial transcriptomics

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ImmunologybioRxivPreprintMar 5, 2025

Unveiling the Immune Landscape of COVID-19 and prolonged Long-COVID through Single-Cell RNA Sequencing

Marta Līva Spriņģe, Kristīne Vaivode, Rihards Saksis…·Vita Rovīte

This study uses single-cell RNA sequencing to analyze immune cell states in COVID-19 and Long-COVID patients, revealing persistent immune dysregulation 1.5-2 years post-infection.

1 citation

humanscRNA-seq

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Cancer BiologyMolecular OncologyPeer-reviewedSep 8, 2024

Digital spatial profiling of RNA in pancreatic neuroendocrine tumors highlights the distinct profile of alpha-SMA positive stroma and its impact on surrounding tumor cells

Helvijs Niedra, Raitis Pečulis, Rihards Saksis…·Vita Rovīte

This study uses digital spatial profiling to analyze gene expression in pancreatic neuroendocrine tumor stroma and tumor cells, revealing distinct profiles and potential crosstalk mechanisms.

11 citations

humanspatial transcriptomics

𝕏 PostBluesky