MicrobiologyInternational Journal of Molecular SciencesPeer-reviewed
SARS-CoV-2 ORF7a mutation found in BF.5 and BF.7 sublineages impacts its functions
Uddhav Timilsina, Emily B. Ivey, Sean R. Duffy…·Spyridon Stavrou
The paper evaluates the effect of the H47Y mutation in ORF7a of SARS-CoV-2 BF.5 and BF.7 sublineages on its three main functions, finding it impairs IFN-I antagonism and MHC-I downregulation but not anti-SERINC5 function.
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