NeurosciencebioRxivPreprint
The adaptor protein DAB2 cell-autonomously links APOE with disease-associated microglia (DAM)/TREM2 state dysregulation associated with Alzheimer's disease
Dervis A Salih, Melissa Barber, William D Andrews…·John Hardy
This study identifies DAB2 as a key regulator linking APOE genotype to microglial state transitions and dementia-risk networks in Alzheimer's disease.
DOI 10.64898/2026.11.12.766141