Souradeep Basu

AlphaGenome predicts functional genomic measurements from DNA sequences with high resolution and accuracy across multiple modalities, outperforming existing methods in variant effect prediction.

This study identifies CKS proteins as multifaceted regulators of the cell cycle by modulating CDK activity and phosphorylation across diverse processes.

This study shows that the hydrophobic patch mediates cyclin-CDK localization to the centrosome, which is essential for mitotic entry and CDK substrate phosphorylation.