Author
BioNTech (Germany)ORCID 0000-0003-4561-2273Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Chaitanya Kurhade, Wei J. Chen, Weiqiang Li…·Kayvon Modjarrad
This study evaluates the immunogenicity of an LP.8.1-adapted BNT162b2 vaccine against JN.1 sublineages, showing higher neutralizing antibody responses compared to other adapted vaccines.
Ayline Kübler, Sophie-Christin Linkenbach, Fulvia Vascotto…·Uğur Şahin
This study shows that lung-targeted cytokine RNA-lipoplexes enhance anti-tumor immunity by activating T and NK cells and reducing Tregs, with efficacy in murine models and human lung tumor cultures.
Wei J. Chen, Kristin R. Tompkins, Ian W. Windsor…·Kayvon Modjarrad
Omicron JN.1- and KP.2-adapted BNT162b2 mRNA vaccines elicit stronger neutralizing antibody responses against circulating sublineages than previous vaccines, supporting annual strain updates.
Kayvon Modjarrad, Ye Che, Wei Chen…·Kena A. Swanson
The monovalent Omicron XBB.1.5-adapted BNT162b2 mRNA vaccine elicits stronger neutralizing antibody responses against XBB.1.5 and related sublineages than the bivalent Wild Type + Omicron BA.4/5 vaccine.
Karim Beguir, Marcin J. Skwark, Yunguan Fu…·Uğur Şahin
A COVID-19 Early Warning System combines structural modelling with machine learning to detect and monitor high risk SARS-CoV-2 variants, identifying all 16 WHO designated variants on average more than one and a half months in advance by selecting on average less than 0.3% of the weekly novel variants.