Carmen W.E. Embregts

The paper shows that competition between NuRD and SWI/SNF chromatin remodelers regulates epithelial-mesenchymal plasticity and inflammation in oral cancer, with CDK2AP1 loss promoting pro-inflammatory responses and macrophage recruitment.

This study investigates MPXV neurotropism and antiviral signaling in CNS cells using human stem cell-derived models, finding that glial cells are more susceptible and exhibit reduced type I IFN responses.