Ziyue Yi

LazyNet is a neural-ODE model for CRISPR single-cell screens that provides interpretable mechanistic insights and competitive performance on neuronal and T-cell datasets.

This paper introduces LazyNet, a model using ResNet with logarithmic/exponential functions to approximate ODEs in biological systems, improving efficiency and reducing reliance on large datasets.

This study shows that 4-PBA reprograms monocytes to resolve inflammation and atherosclerosis by altering adhesion and increasing anti-inflammatory markers.