Author

Jane L. Buchanan

University of IowaORCID 0000-0003-4886-5372Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adam J. RauckhorstiD· 1 shared Eric B. TayloriD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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1 shared paperBiochemistry

Adam J. RauckhorstORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJul 10, 2023

3-hydroxykynurenine is a ROS-inducing cytotoxic tryptophan metabolite that disrupts the TCA cycle

Jane L. Buchanan, Adam J. Rauckhorst, Eric B. Taylor

This study identifies 3-hydroxykynurenine as a cytotoxic tryptophan metabolite that disrupts the TCA cycle and induces ROS-mediated apoptosis in colon cancer cells.

15 citations

humanmetabolomics

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