Claudio Luchini

This study identifies three distinct spliceosomic profiles in pancreatic neuroendocrine tumors linked to clinical and molecular characteristics and potential therapeutic targets.

This study traces the clonal evolution of pancreatic cancer from IPMN using genomic and transcriptomic data, identifying two distinct evolutionary trajectories and their implications for PDAC progression.

This study identifies a diet-imprinted macrophage-tumor circuit driven by the CAMP-P2RX7 axis that promotes pancreatic cancer initiation, plasticity, and metastasis.

This study profiles proteins and glycoproteins in pancreatic neoplasms to identify expression patterns and potential progression markers.

This study identifies MAPK signalling as defining fibroblast subtypes in pancreatic cancer, linking MAPKhigh CAFs to poor prognosis and immune evasion.