Marcel Kretschmer

This study shows that Pseudomonas aeruginosa membrane vesicles inhibit mitochondrial complex III, activate AMPK signaling, and reduce global protein synthesis in human lung cells.

This study introduces a method to quantify bacterial membrane vesicles using FM4-64 dye and linear regression, showing its superiority over protein-based methods and identifying a key regulator in vesicle-mediated pathogenesis.