BiochemistryPNAS NexusPeer-reviewed
Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons
Germanna Lima Righetto, Yanting Yin, David M. Duda…·Levon Halabelian
This study characterizes DCAF12 interactions with MAGEA3 and CCT5 degrons using biophysical assays and cryo-EM, revealing key residues for degron recognition and informing PROTAC design.