Author

David M. Duda

Janssen Research & Development (United States)

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Biochemistry· 1

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Approach:biophysical modeling· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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Aaron N. PatrickiD· 1 shared Alma Seitova· 1 shared Charu ChaudhryiD· 1 shared Dalia Baršytė-LovejoyiD· 1 shared Germanna Lima RighettoiD· 1 shared Hong ZengiD· 1 shared Jean-François BrazeauiD· 1 shared Levon HalabelianiD· 1 shared

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Aaron N. PatrickORCID

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1 paper

Recent·Most cited

BiochemistryPNAS NexusPeer-reviewedMar 28, 2024

Probing the DCAF12 interactions with MAGEA3 and CCT5 C-terminal degrons

Germanna Lima Righetto, Yanting Yin, David M. Duda…·Levon Halabelian

This study characterizes DCAF12 interactions with MAGEA3 and CCT5 degrons using biophysical assays and cryo-EM, revealing key residues for degron recognition and informing PROTAC design.

5 citations

structural biologybiophysical modeling

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