huili wang

This study shows that aging-related changes in cysteine posttranslational modifications alter protein phase separation, leading to aggregation and neurodegeneration.

The paper investigates electrical signaling between mid-capillary pericytes and endothelial cells in the neurovascular unit, showing syncytial coupling and its role in transmitting seizure-associated signals without relying on VGCCs.

The paper shows that Intersectin-1 and Endophilin A1 form condensates near synaptic release sites to cluster replacement vesicles, enabling rapid replenishment of neurotransmitter release sites.

The paper quantifies viscoelastic properties of synapsin condensates in live cells and identifies α-synuclein's role in regulating their material state.