Author

Buket Sağlam

Izmir Institute of TechnologyORCID 0009-0000-9991-3042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Azime Akçaöz-AlasariD· 2 shared Bünyamin AkgüliD· 2 shared Ahmet Batuhan Dondurur· 1 shared Dilek Cansu GüreriD· 1 shared Ekin YILDIZiD· 1 shared İpek ErdoğaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

Azime Akçaöz-AlasarORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 20, 2026

METTL3 modulates cell viability and motility in HCC1143 and MDA-MB-231 triple-negative breast cancer cells

Buket Sağlam, Azime Akçaöz-Alasar, Ahmet Batuhan Dondurur…·Bünyamin Akgül

This study investigates METTL3's role in TNBC cell lines, finding it reduces cell viability and impairs motility, particularly in low-metastatic HCC1143 cells through G2/M arrest and actin dynamics disruption.

DOI 10.64898/2026.07.18.739327

humanbulk RNA-seq

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Cancer BiologyTURKISH JOURNAL OF BIOLOGYPeer-reviewedFeb 27, 2024

Expression patterns of m6A RNA methylation regulators under apoptotic conditions in various human cancer cell lines

Azime Akçaöz-Alasar, Buket Sağlam, İpek Erdoğan, Bünyamin Akgül

The paper examines how m6A RNA modifier expression changes under apoptotic conditions in cancer cell lines, finding differential responses to cisplatin and TNF-.

7 citations

humanbulk RNA-seq

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