Cancer BiologyCancer ResearchPeer-reviewed
EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes
Yeying Huang, R. Taylor Durall, Nhi M. Luong…·Christopher Alexander French
This study identifies EZH2 as a dependency in NUT carcinoma, showing that combining EZH2 and BET inhibitors synergistically blocks tumor growth and prolongs survival.