Author

Zhichao Tang

University of ChicagoORCID 0009-0001-8363-3342Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jingxin WangiD· 2 shared Anjie ZheniD· 1 shared Anna LewickaiD· 1 shared Anne CooperiD· 1 shared Chang Qi· 1 shared Chenguang YuiD· 1 shared David K. JohnsoniD· 1 shared Diyun SuniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Jingxin WangORCID

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2 papers

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedJun 5, 2025

Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges

Shalakha Hegde, Sana Akhter, Zhichao Tang…·Jingxin Wang

This study identifies coumarin derivatives that selectively bind RNA single G bulges, revealing key structural features and using computational and experimental methods to guide rational ligand design.

6 citations

proteomicsdeep learning

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Pharmacology & ToxicologyACS Medicinal Chemistry LettersPeer-reviewedApr 12, 2024

Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STINGA230 Variants

Zhichao Tang, Junxing Zhao, Ying Li…·Jingxin Wang

The paper characterizes BDW568, a non-nucleoside STING agonist, showing it activates STINGA230 variants in human cells and mimics endogenous ligands.

2 citations

humanproteomics

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